INFLUENCE OF CHRONIC CIGARETTES SMOKING ON SERUM TESTOSTERONE AND PROLACTIN LEVELS AMONG SUDANESE SMOKERS

Mowada M. Elmleeh, AbdElkarim A. Abdrabo Objective: to estimate testosterone and prolactin levels in chronic Sudanese smokers regardless of their fertility functions. Materials and methods: the study was conducted at Omdurman area-Khatoum state-Sudan during the period from December 2012 to March 2013, it involved a control group of apparently healthy non smokers (N=50) matched for…

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EVALUATION OF RENAL FUNCTIONS IN SUDANESE PATIENTS WITH THYROID DISORDERS

Sara Abdalseed Hamed, AbdElkarim A. Abdrabo  Background: Thyroid dysfunction causes significant changes in kidney function. Both hypothyroidism and hyperthyroidism affect renal blood flow and glomerualr filteration rate (GFR). Aim: to evaluate serum creatinine, urea, and creatinine clearance concentrations in patients with thyroid dysfunctions. Materials and Methods: the study involved a control group of apparently healthy…

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ELUCIDATION OF IRON BINDING PATTERNS THROUGH INSILICO APPROACHES IN HUMAN IRON BINDING PROTEINS

Muthukumaran Sivashanmugam, Anusha Kuppuswamy , Umashankar Vetrivel , K.N. Sulochana  Human iron binding proteins play a crucial role in various cellular activities. Cellular iron imbalance can lead to many disease conditions. A comprehensive understanding of iron binding patterns in proteins is necessary to develop proper therapeutic interventions. By this study, we have collated the present…

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MECHANISM OF ACTION OF ANTI-DIABETIC PROPERTY OF CINNAMIC ACID, A PRINCIPAL ACTIVE INGREDIENT FROM THE BARK OF CINNAMOMUM CASSIA.

Ruchi Tandon , Anurag Gupta, Abhijit Ray Glucose lowering potential of Cinnamon extracts is reported in a variety of studies and experimental models. Cinnamic acid is one of the main constituents, isolated from the bark of Cinnamomum cassia and is known to possess anti diabetic properties.  In the present manuscript, we are reporting  in vitro…

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EFFECTS OF DUAL TASK TRAINING ON BALANCE AND COGNITION IN COMMUNITY DWELLING ELDERLY MALES AND FEMALES LIVING IN KANPUR, U.P.

Vanshika Sethi and Shivangi Saxena ABSTRACT Introduction: Aging in its broadest sense is the continuous and irreversible decline in the efficiency of various physiological processes1. A decline in all major systems for e.g. cardiovascular, metabolic, respiratory and neuromuscular contributes to weakness, fatigue and slowing of movement that has been the hallmarks of ageing.3Among older adults…

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DEVELOPMENT AND CHARACTERIZATION OF NON-IONIC SURFACTANT VESICLES (NIOSOMES) FOR ORAL DELIVERY OF NORFLOXACIN

Akhilesh Dubey, Prabhakara Prabhu  Controlled release drug products are often formulated to permit the establishment and maintenance of drug concentration at target site for longer interval of time. One such technique of drug targeting is ‘niosome’. Niosomes are non-ionic surfactant vesicles obtained on hydration of synthetic nonionic surfactants, with or without incorporation of cholesterol or…

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EFFECT OF SOLUBILITY OF DIFFERENT EXCIPIENTS ON DRUG RELEASE OF CHITOSAN MATRIX TABLET OF ACECLOFENAC: A STUDY

Ramesh G. Katedeshmukh, Adhikrao V. Yadav Until now numerous oral controlled drug delivery systems have been developed to prolong drug release. The crucial point in this respect is that the drug has to be absorbed well throughout the whole gastrointestinal tract. Chitosan, a linear binary heteropolysaccharide, composed of β-1, 4-linked glucosamine (GlcN) with various degrees…

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ANCIENT AND RECENT MEDICINAL USES OF CUCURBITACEAE FAMILY

Shweta S. Saboo , Priyanka K. Thorat , Ganesh G. Tapadiya , S S. Khadabadi The  family  Cucurbitaceae  includes  a  large  group  of  plants  which  are  medicinally valuable.  It  is  a  family  of  about  130  genera  and  about  800  species.  Seeds  or  fruit parts  of  some  cucurbits  are  reported  to  possess  purgatives,  emetics  and  …

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