COMPARATIVE BIOCHEMICAL STUDIES ON THE POISON GLAND AND POISON SAC OF THE WORKER BEES OF THREE DIFFERENT APIS SPECIES (APIS DORSATA, APIS MELLIFERA AND APIS FLOREA)

Neelima R Kumar, Anita Devi, Kriti Handa & Namita ABSTRACT In Hymenoptera glands associated with the sting apparatus of worker honey bee produce venom which is known to be composed of a wide spectrum of biomolecules ranging from biogenic amines to peptides and proteins. The anatomy of “Venom apparatus” reveals the presence of two important…

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FAST DISSOLVING DOSAGES FORM: BOON TO EMERGENCY CONDITIONS

Md. Nawaz Alam, Sanjay K. Sharma, Manish Jaimini, Shailender Mohan & Arindam Chatterjee ABSTRACT Recent advancements made in oral drug delivery technology prompted researchers and scientists to develop oral disintegrating tablets with improved patient convenience and compliance. FDTs have gained considerable attention especially for those patients who have difficulties in swallowing owing to dysphasia, hand…

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CISPLATIN INDUCED REPRODUCTIVE TOXICITY AND ITS MODULATION BY ANDROGRAPHIS PENICULATA IN SWISS ALBINO MICE

Sant Suman Rastogi, Mandavi Singh, Uttam Shrestha ABSTRACT Cisplatin is an anticancer drug used against various types of epithelial cancers which produces reproductive toxicity when used during pregnancy. Andrographis paniculata is a popular herb in Asia and South East Asia which is traditionally used for treatment of diabetes, hypertension and sore throat. The present study…

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CYTOGENETIC RESPONSE OF IMATINIB MESYLATE IN NEPALESE CHRONIC MYELOID LEUKEMIA PATIENTS IN CHRONIC PHASE

Krishna Deo Sharma, Chandra Bhushan Jha, Prahlad Karki, Ajaya Jang Kunwar, Sunil Dhungel, Dhiraj Maskey ABSTRACT Background: The cause of chronic myeloid leukemia (CML) is the Philadelphia (Ph) chromosome formed by a reciprocal translocation between chromosomes 9 and 22 giving rise to a constitutively active BCR-ABL tyrosine kinase. Imatinib Mesylate inhibits this kinase in newly…

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