POTENTIAL ROLE OF ANTIOXIDANTS IN CANCER MANAGEMENT

Sajal Kumar Jha, Roopa Karki, Amitava Ghosh ABSTRACT Cancer has a complex etiology with multiple risk factors that involve the interplay between genetic and environmental influences. Epidemiological studies show that a high intake of antioxidant-rich foods is inversely related to cancer risk. Among a number of mechanistic hypotheses, diet-derived antioxidants have been proposed to contribute…

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FORMULATION AND GAMMA SCINTIGRAPHIC EVALUATION OF COLON SPECIFIC TINIDAZOLE TABLETS IN HEALTHY HUMAN VOLUNTEERS

Bhawna Gauri, Dimple Chopra, Shailendra K Singh, Lovekesh Nagpal ABSTRACTThe objective of our study was to develop single-unit colon targeted drug delivery system of tinidazole using pH dependent methacrylic acid polymers and/or time dependent polymeric combination, which slowly release the drug to colon. Lactose-based tinidazole placebo tablets were coated using various ratios of two co-polymers,…

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ADVENTS IN CONTRACEPTION : IMMUNOCONTRACEPTION

Jyotsana Dwivedi, Sachdev Yadav Abstract Immunocontraception is one of youngest branch of immunology and represents the novel approach to the development of family planning methods. Investigations on Immunocontraception field endure in last hundred years due to revolutionary advancement was made with apparition of genetic, molecular biology and reproductive immunology. Such products would have many advantages…

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NEUROPROTECTIVE ROLE AND ANTI-AMNESIC EFFECT OF DOCOSAHEXAENOIC ACID AND GAMMA-LINOLENIC ACID IN LEAD INDUCED NEUROLOGICAL DEFICIT AND AMNESIA IN SWISS ALBINO MICE.

S. Yadav, V. Sharma Lead is virtually toxic to every organ of body including central nervous system where it may manifest as encephalopathy’s and neuropathies, but also various behavioral changes indicative of cerebral dysfunction like; periodic convulsions, irritability, hyperactivity, retardation of normal development, emotional instability, behavioral disorders, low attention span, impaired motor development, and antisocial…

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