EVALUATION OF ANTHELMINTIC ACTIVITY USING SOLVENT EXTRACT OF PADINA TETRASTROMATICA IN INDIAN EARTHWORM (PHERETIMA POSTHUMA)

B. Clara Gnana Selvi and Amutha Santhanam

ABSTRACT

The anthelmintic activities of different solvent extracts of Padina tetrastromatica were evaluated on Indian adult earthworms Pheretima posthuma (Annelida). Different concentrations (50 and 100 mg/ml) of methanolic, diethyl ether and aqueous extracts were evaluated for anthelmintic activity by recording the time required for paralysis and death of earthworms. The activities were compared with the standard drug Albendazole. Dose-dependent activity was observed in the solvent extracts of seaweed. However, the methanolic extract of seaweed Padina tetrastromatica showed significant anthelmintic activity than the standard drug.

Keywords: Padina tetrastromatica, Pheretima posthuma, Anthelmintic, Methanolic extract.


PDF