NEUROPHARMACOLOGICAL SCREENING OF ZAMZAM WATER REVEALED ITS ANXIOLYTIC AND ANTIDEPRESSANT EFFECT

Rahila Najam, Bushra Riaz

ABSTRACT

Introduction: ZamZam water is utilized by Muslims either medicinally or religiously. ZamZam water has therapeutic potential and it can be further assessed for its restorative effects.

Material and method: The purpose of this study is to check the pharmacological and therapeutic action of ZamZam. For this purpose collection of zamzam was done from Mecca, Saudiarabia and neuropharmacological screening of zamzam water was done. Among CNS screening test, cage crossing test, Open field test, Stationary rod test, Head Dip Test, Passive avoidance test and Forced Swim Test were performed.

Result: It was analyzed that ZamZam water is anxiolytic in acute administration and antidepressant after long term dosing. Zamzam water decrease exploration and increase learning and memory.

Keywords: Zamzam water, anxiolytic, antidepressant, exploration.


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