Subhashish Das, Harendra Kumar
ABSTRACT
Background : As per the current quality control standards the platelets can be assessed by using several parameters such as swirling, volume, platelet count and WBC count per bag and pH changes which in-turn have also been endorsed by The American Association of Blood Banks (AABB). In recognizing the limited capacity of transfusion services to perform a wide array of checks, AABB has restricted the basic minimum requirements to at least include the platelet count, pH, volume, red cell content, and residual WBC count respectively.
Materials and Methods: 625 random donors platelets were studied after obtaining the written consent. The results were analyzed by the analysis of the variance (ANOVA) and a two-tailed Students test.
Results: The pH values showed a significant fall over 7 days of storage but were within the acceptable limits. Over the these seven days of storage period, significant changes in Po2 values Pco2 was observed along with the LDH levels.
Conclusion: Therapeutic storage of platelet concentrate remains a challenge and hence this study was carried out with the aim of improving the duration of storage of platelet concentrates.
Key words: platelet concentrate, biochemical parameters, pH, storage lesions.