Mowada M. Elmleeh, AbdElkarim A. Abdrabo
Objective: to estimate testosterone and prolactin levels in chronic Sudanese smokers regardless of their fertility functions.
Materials and methods: the study was conducted at Omdurman area-Khatoum state-Sudan during the period from December 2012 to March 2013, it involved a control group of apparently healthy non smokers (N=50) matched for age with a test group of smokers (N=50). The range of both groups was 20-60 years old. Serum testosterone and prolactin levels were measured in Omdurman Military hospital by using ELISA full automated human analyzer (Human-Germany). Appropriate statistical tests were used to asses’ significant differences in the means of the studied concentrations between smokers and control group.
Results: The smokers showed lower levels of testosterone [M±SD =3.0±1.9ng/ml] compared with control group [M±SD = 6.1±2.8ng/ml], this difference was considered statistically significant [P = 0.03 which is less than 0.05]. While there is no significant differences in prolactin levels in smokers [M±SD = 7.3± 2.0ng/ml] compared with control group [M±SD = 7.6±1.8ng/ml P = 0.83 which is higher than 0.05].
Conclusion: The study added further evidence for possible harmful consequence of smoking on lowering the testosterone levels which will affect on male mass muscles as much as male fertility functions in the future.
Key words: Cigarette, nicotine, respiratory, cardiovascular, testosterone, prolactin