Mayuri Khare, Poonam Singh and Vinod Singh
ABSTRACT
Hypothyroidism is an endocrine syndrome due to which the metabolic rate of the body system is affected. The disorder and the changes are due to the imbalance in the hormone secretion which is responsible for thyroiditis. Other disorders like hypertension, diabetes caused due to hormonal changes are all linked, directly or indirectly to the syndrome. The association between the thyroid hormones and the stress hormones is less understood. We investigated a total 50 subjects of which 25 were eligible for further study. The level of TSH, T3, T4, Cortisol and prolactin were determined using ELISA following standard protocol. The study reveled that level of TSH (80%), T3 (70%) and T4 (60%) are comparatively higher from their normal values. Cortisol and prolactin were in normal range. Our findings suggests that excess thyroid hormones may induce tissue injury secondary to production of other hormones in excess thus leading to many other disorders and majorly affecting the metabolism in vertebrates.
Keywords: hypothyroidism, hormones, ELISA, stress