ESTIMATION OF SERUM URIC ACID LEVEL IN PREECLAMPTIC PREGNANT SUDANESE WOMEN

Mutasem Mahmmoud Abdallah, Abdel Rahim M. Muddathir, AbdElkarim A.Abdrabo

ABSTRACT
Background
An elevated level of uric acid during pregnancy has been considered a predictable tool for preeclampsia during the third pregnancy trimester. We investigated uric acid levels in preeclampsia women during their third trimester to validate the hypothesis and these outcomes stratified by presence of hyperuricaemia at delivery at all preeclampsia patients and the normal levels of the healthy ones.
Methods
During the period from April 2013 to September 2013, 200 blood samples were collected from pregnant ladies attending Jubal Awlia and Omdurman Maternity Hospital-Khartoum-Sudan, 100 of them were with symptoms of preeclampsia and 100 were normal pregnant included as control.
Uric acid was measured in maternal serum using uric acid enzymatic kit. All data was analyzed by computerized statistic program SPSS.
Results
The mean value of systolic and diastolic blood pressures in pregnant ladies with preeclampsia is higher (M±SD=149.4±24.3 for systolic, and 108.8 ±11.5 for diastolic), compared to normal pregnant ladies (M±SD=125.4±12.5 for systolic, and 86.1±5.4 for diastolic), (P= 0.000). Serum uric acid was higher in preeclampsia pregnant ladies compared to normal pregnant ladies (M±SD= 8.5±3.5, and 4.0±0.9 respectively, P=0.000).

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