Yadav G, Jha C B, Baral P, Pandey N, Awasthi J R
ABSTRACT
Background: Heat stress is one of the most important stressors especially in hot regions of the world. Adaptation to heat stress requires the physiological integration of many organs and systems viz. endocrine, cardio respiratory and immune system. The aim of the study was to observe the effect of heat stress on rat’s kidney.
Materials and Methods: The study was conducted in sixty adult albino rats at department of human anatomy, BP Koirala Institute of Health Sciences, Dharan, Nepal. Rats were randomly divided into two groups i.e. control and experimental each consisting of 30 rats. Rats belonging to control group and experimental group were kept in controlled room temperature of 25±0.5 0 C and 35 ±0.5 0 C for two weeks. On 15th day all rats sacrificed and both kidneys from each rat were removed.
Results: Heat stress caused decrease in body weight, kidney weight and volume of kidney. Histological study showed decrease in diameter of renal corpuscle, glomerulus, proximal convoluted tubule, distal convoluted tubule and increase in dimension of Bowman’s space.
Conclusion: Heat stress caused both morphological and histological changes in kidney.
Key words: Kidney, heat stress, rats, light microscopy and histology.