THE pH ESTIMATION IN STORED PLATELETS: AN INSTITUTIONAL STUDY

Subhashish Das, Harendra Kumar

ABSTRACT
Background : As per the current quality control standards the platelets can be assessed by using several parameters  such as swirling, volume, platelet count and WBC count per bag and pH changes which  in-turn have also been endorsed by The American Association of Blood Banks (AABB). In recognizing the limited capacity of transfusion services to perform a wide array of checks, AABB has restricted the basic minimum requirements to at least include the platelet count, pH, volume, red cell content, and residual WBC count respectively.
Materials and Methods: 625 random donors platelets were studied after obtaining the written consent. The results were analyzed by the analysis of the variance (ANOVA) and a two-tailed Students   test. 
Results: The pH values showed a significant fall over 7 days of storage but were within the acceptable limits. Over the these seven days of storage period, significant changes  in  Po2 values  Pco2 was observed along with the LDH levels.    
Conclusion: Therapeutic storage of platelet concentrate remains a challenge and hence this study  was carried out with the  aim of improving the duration of storage of platelet concentrates.   
Key words: platelet concentrate, biochemical parameters, pH, storage lesions. 

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