Qing-Yong Wang, Rong-Hai Li, Bei Song, Xiao-Hong Shang
ABSTRACT
It is important for microbiological workers to perform periodic surveillances on the emergence of isolates from positive blood cultures and their antibiotic resistance. The aim of this study is to evaluate the common pathogenic distribution and antimicrobial susceptibility of pathogens isolated from aerobic and anaerobic bottles for the past six years. From January 2010 to December 2015, 9122 bottles were tested using an automated blood culture detection system. From 9122 bottles, 745 positive bottles yielded 450 organisms. Of these, 250 (55.6%) were Gram-negative bacteria, 184 (40.9%) were Gram-positive bacteria and 16 (3.6%) were fungi. Escherichia coli and Staphylococcus spp were the most frequently isolated species for Gram-negative and Gram-positive bacteria, respectively. Amikacin, meropenem, imipenem, vancomycin, linezolid and quinupristin-dalfopristin may be the best choices to use for positive blood cultures in the hospital. The periodic surveillance of the common pathogenic distribution isolated from bottles and their antimicrobial susceptibilities can help medical workers to recognize the emergence and rapid dissemination of pathogens with high rates of resistance to most commonly used antibiotics.
Key Words: Blood culture; Species distribution; Antimicrobial susceptibility.