Anupama Bhadauria, Rakesh P. Patel<\/p>\n
ABSTRACT:
In the recent times nanotechnological innovations have been applied extensively in finding solutions to problems encountered during conventional cancer therapy and diagnosis- mainly catering to drug targeting and minimizing concomitant adverse effects. From the first studies on liposome-encapsulated drug nanoparticles, progressing through PEGylation to incorporation of biomarkers on the surface, the field has continuously evolved to accommodate newer technologies like gene therapy using Rexin-G, delivering silencing RNA by \u00e2\u20ac\u0153Trojan horse\u00e2\u20ac\u009d approach to the tumour cells, thermal destruction of the cancerous cells using Kanzius machine and gold nanoparticles. On similar lines, semiconductor-stuffed nanoparticles called quantum dots have improved cancer detection by leaps and bounds. The field of nanotechnology continues to excite<\/span> the researchers for its immense and untapped utility towards cancer therapy and diagnosis, as witnessed in form of undertrial projects like the formulation of novel BIND-014 nanoparticle, cyclodextrin-based nanoparticle, chemically<\/span> engineered adenovirus-nanoparticle for stimulating the immune system and another one used as a magnetic resonance imaging contrast agent, among others. Commercialization of recyclable, microemulsion-based nanoparticles is still underway, which could possibly be a significant step towards eco-friendliness<\/span> and cost reduction.
KEYWORDS<\/span>: Nanoparticle, nanotechnology, carbon<\/span> nanotube, cancer, tumour.<\/p>\n