{"id":207,"date":"2013-08-10T00:00:00","date_gmt":"2013-08-10T00:00:00","guid":{"rendered":"http:\/\/npaa.in\/journal-ijta\/evaluation-of-renal-functions-in-sudanese-patients-with-thyroid-disorders\/"},"modified":"2019-09-22T10:29:49","modified_gmt":"2019-09-22T10:29:49","slug":"evaluation-of-renal-functions-in-sudanese-patients-with-thyroid-disorders","status":"publish","type":"post","link":"https:\/\/npaa.in\/journal-ijta\/2013\/08\/10\/evaluation-of-renal-functions-in-sudanese-patients-with-thyroid-disorders\/","title":{"rendered":"EVALUATION OF RENAL FUNCTIONS IN SUDANESE PATIENTS WITH THYROID DISORDERS"},"content":{"rendered":"<p>Sara Abdalseed Hamed, AbdElkarim A. Abdrabo<\/p>\n<div>\u00a0Background: <span class=\"cm_word\" style=\"border-bottom: 1px solid #0000FF !important;text-decoration:underline !important;color:#0000FF !important\">Thyroid dysfunction<\/span> causes significant changes in kidney function. Both hypothyroidism and hyperthyroidism affect renal blood flow and glomerualr filteration rate (GFR). Aim: to evaluate serum creatinine, urea, and <span class=\"cm_word\" style=\"border-bottom: 1px solid #0000FF !important;text-decoration:underline !important;color:#0000FF !important\">creatinine clearance<\/span> concentrations in patients with thyroid dysfunctions. Materials and Methods: the study involved a control group of apparently healthy (euthyroid) (N = 90) matched for age with a test group of patients with thyroid dysfunctions (N = 96). The age range of both groups was 25-63 years. Serum creatinine, urea, and creatinine clearance concentrations were measured according to the standards. <span class=\"cm_word\" style=\"border-bottom: 1px solid #0000FF !important;text-decoration:underline !important;color:#0000FF !important\">Appropriate<\/span> statistical tests were used to assess significant difference in the means of the studied concentrations between patients and the control group. Results: The hypothyroid patients showed significantly higher serum creatinine (M\u00c2\u00b1SD = 1.04\u00c2\u00b10.15 mg\/dl), level compared with euthyroid (M\u00c2\u00b1SD =0.97\u00c2\u00b10.17, P =0.033), and reduced creatinine clearance (M\u00c2\u00b1SD = 93\u00c2\u00b113.6 ml\/min, and 101\u00c2\u00b110.9 ml\/min, respectively, P = 0.004). In hyperthyroid patients, serum creatinine concentrations were not differed (M\u00c2\u00b1SD = 0.98\u00c2\u00b10.19 mg\/dl) compared with the euthyroid group (M\u00c2\u00b1SD = 0.97\u00c2\u00b10.17mg\/dl, P = 0.16). Creatinine clearance was significantly higher in hyperthyroid compared with euthyroid (M\u00c2\u00b1SD = 125\u00c2\u00b115 ml\/min, and 101\u00c2\u00b110 ml\/min, respectively, P = 0.006).<\/div>\n<div>Blood urea concentrations were not significantly different in the studied groups\u00a0<\/div>\n<div>Conclusion: the study added further evidences for <span class=\"cm_word\" style=\"border-bottom: 1px solid #0000FF !important;text-decoration:underline !important;color:#0000FF !important\">the possible changes<\/span> that can occurs in <span class=\"cm_word\" style=\"border-bottom: 1px solid #0000FF !important;text-decoration:underline !important;color:#0000FF !important\">renal functions<\/span> in patients with <span class=\"cm_word\" style=\"border-bottom: 1px solid #0000FF !important;text-decoration:underline !important;color:#0000FF !important\">thyroid disorders<\/span>, especially GFR.\u00a0<\/div>\n<div><\/div>\n<p><a href=\"https:\/\/npaa.in\/journal-ijta\/admin\/ufile\/1376284475IJTA_10_7-10.pdf\">PDF<\/a><\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sara Abdalseed Hamed, AbdElkarim A. Abdrabo \u00a0Background: Thyroid dysfunction causes significant changes in kidney function. Both hypothyroidism and hyperthyroidism affect &hellip; <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,21],"tags":[],"class_list":["post-207","post","type-post","status-publish","format-standard","hentry","category-10","category-volume-10"],"_links":{"self":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts\/207","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/comments?post=207"}],"version-history":[{"count":2,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts\/207\/revisions"}],"predecessor-version":[{"id":884,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts\/207\/revisions\/884"}],"wp:attachment":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/media?parent=207"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/categories?post=207"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/tags?post=207"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}