{"id":429,"date":"2016-02-26T00:00:00","date_gmt":"2016-02-26T00:00:00","guid":{"rendered":"http:\/\/npaa.in\/journal-ijta\/etanercept-in-chronic-plaque-psoriasis\/"},"modified":"2019-09-22T11:06:07","modified_gmt":"2019-09-22T11:06:07","slug":"etanercept-in-chronic-plaque-psoriasis","status":"publish","type":"post","link":"https:\/\/npaa.in\/journal-ijta\/2016\/02\/26\/etanercept-in-chronic-plaque-psoriasis\/","title":{"rendered":"ETANERCEPT IN CHRONIC PLAQUE PSORIASIS"},"content":{"rendered":"<p>Ramasamy P.P, Bharathi .S, Swarnalakshimi .S, Madhavan.R.<\/p>\n<p class=\"MsoNormal\" style=\"margin-bottom: 6pt; text-align: justify;\"><b><span style=\"mso-bidi-font-size:10.0pt;mso-ascii-font-family:Calibri;mso-hansi-font-family: Calibri;mso-bidi-font-family:Calibri;color:#4F81BD;mso-themecolor:accent1\">ABSTRACT<\/span><\/b><\/p>\n<p class=\"MsoNormal\" style=\"margin-bottom: 6pt; text-align: justify;\"><span style=\"font-size: 10pt; text-indent: 0.2in;\">Psoriasis is a chronic inflammatory disease with frequent relapses and remissions. The introduction of biologicas increased the remission periods, decreases relapse and hence improve the quality of life.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-bottom: 6pt; text-align: justify;\"><b><span style=\"font-size:10.0pt;mso-ascii-font-family:Calibri;mso-hansi-font-family: Calibri;mso-bidi-font-family:Calibri\">Method<\/span><\/b><span style=\"font-size: 10.0pt;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family: Calibri\">: The study includes 17 adult patients of chronic plaque psoriasis, <span style=\"color:#333333\">who received etanercept subcutaneously at a\u00a0<\/span>dosage\u00a0<span style=\"color:#333333\">of 50 mg once weekly for 24 weeks, followed by 6 months follow up. <o_p><\/o_p><\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-bottom: 6pt; text-align: justify;\"><b><span style=\"font-size:10.0pt;mso-ascii-font-family:Calibri;mso-hansi-font-family: Calibri;mso-bidi-font-family:Calibri;color:#333333\">Results:<\/span><\/b><span style=\"font-size:10.0pt;mso-ascii-font-family:Calibri;mso-hansi-font-family: Calibri;mso-bidi-font-family:Calibri;color:#333333\">\u00a0 <\/span><span style=\"font-size:10.0pt; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family: Calibri;color:black\">At the end of 12 weeks 8 patients (47.05%) achieved more than 75% reduction of PASI and at the end of 24 weeks 9 patients(52.94%) achieved more than 75% reduction of PASI.<\/span><span style=\"font-size:10.0pt; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family: Calibri;color:#333333\"> <o_p><\/o_p><\/span><\/p>\n<div style=\"text-align: justify;\"><b style=\"font-weight: bold;\"><span style=\"font-size:10.0pt; line-height:115%;font-family:\"Calibri\",\"sans-serif\";mso-fareast-font-family: \"Times New Roman\";mso-fareast-theme-font:minor-fareast;mso-ansi-language:EN-US; mso-fareast-language:EN-US;mso-bidi-language:AR-SA\">Conclusion<\/span><\/b><span style=\"font-size: 10pt; line-height: 115%; font-family: Calibri, sans-serif;\"><b>:\u00a0 <\/b>Our study shows that <span style=\"color: rgb(51, 51, 51);\">etanercept has good efficacy without any significant side effects and it should be considered in patients with moderate to severe chronic plaque psoriasis not responding to other conventional\u00a0 modes of therapy.<\/span><\/span><\/div>\n<div><span style=\"font-size:10.0pt;line-height:115%;font-family:\"Calibri\",\"sans-serif\"; mso-fareast-font-family:\"Times New Roman\";mso-fareast-theme-font:minor-fareast; mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA\"><span style=\"color:#333333\"><br \/><\/span><\/span><\/div>\n<p><a href=\"https:\/\/npaa.in\/journal-ijta\/admin\/ufile\/1456474727IJTA_31_18-21.pdf\">PDF<\/a><\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ramasamy P.P, Bharathi .S, Swarnalakshimi .S, Madhavan.R. ABSTRACT Psoriasis is a chronic inflammatory disease with frequent relapses and remissions. The &hellip; <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,37],"tags":[],"class_list":["post-429","post","type-post","status-publish","format-standard","hentry","category-6","category-volume-31"],"_links":{"self":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts\/429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/comments?post=429"}],"version-history":[{"count":2,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts\/429\/revisions"}],"predecessor-version":[{"id":1106,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/posts\/429\/revisions\/1106"}],"wp:attachment":[{"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/media?parent=429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/categories?post=429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/npaa.in\/journal-ijta\/wp-json\/wp\/v2\/tags?post=429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}