Srishty Goyal, Amrish Chandra
ABSTRACT
Statins are the most common drugs prescribed by doctors for lowering the levels of cholesterol or lipids in blood. These drugs are used for low-density lipoprotein concentration in plasma. These are also known as 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors. Statins are also used in cardiovascular ailments risk management. With many benefits of statins, certain side effects are linked with their use with varying degree of severity such as rhabdomyolysis associated with Cerivastatin that lead to its withdrawal from the market in 2001. In today’s world, statins have come a long way from when the first statin being lovastatin was commercialized in 1987. At present, statins are a large part of present pharmaceutical market around the globe.
Key words: Statins, 3-hydroxy-3-methylglutaryl-Co-A reductase inhibitors, Types, Side effects, Safety